Asymmetric pupils or changes in pupillary response to light can indicate diseases of the brain. Multiple sclerosis, for example, often manifests first with inflammation of the optic nerve. The most important and crucial clinical test of such inflammation is the relative afferent pupillary deficit, a change in the pupil's response to light.
We perform clinical pupil testing, quantitative afference testing with filter glasses, experimental pupillography, and pharmacological pupil testing.
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